This generally occurs during the menstrual cycle, pregnancy or after childbirth, and menopause. Women in vulnerable urban affected by depression than men because of the double burden. They must work and be sued care of the household well. Treatment Many people with ill-treatment of depression. Therefore, patients generally less recognized symptoms of depression, the disease tends to focus on somatic or physical complaints, do not understand the consequences of untreated depression, the limited health services, and the stigma.

While health workers have less knowledge about depression and its treatment, lack of control interpersonal skills to face the emotional disturbances, difficult to diagnose depression. Insurance system for mental disorders is still not going well. There are several treatment options for patients, ie farmakoterapi, psychotherapy, or counseling and electroconvulsive therapy (ECT). Sometimes less effective Farmakoterapi  because 52 percent of general practitioners using a lower dose than recommended. Approximately 40 percent of doctors general and seven percent of psychiatrists to prescribe a period shorter than the period of treatment recommendations minimum sustainable.

Maintenance therapy with antidepressants could reduce the risks involved recurrence of Depression Symptoms. This should be accompanied by ongoing treatment with antidepressants for reduce the likelihood of recurrence by 70 percent compared to patients who stop issuing medicine. Considered effective antidepressant for working better and faster than nonpsikofarmaka.